ISSN-registered · Peer-reviewed · Open Access
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Peer-Reviewed · Open Access

The Journal of Molecular Biology

ISSN 2995-8601 Open Access
CROSSREFOPEN ACCESSPEER-REVIEWED
DOICrossref
CC-BYOpen License
OAOpen Access
Peer-Reviewed

Aims & Scope

The Journal of Molecular Biology is a peer-reviewed, open-access journal from Directive Publications, dedicated to research on the molecular machinery of life. It publishes original work on gene expression and regulation, DNA replication and repair, RNA biology, and protein structure and function.

We welcome original research articles, reviews, methods papers, case reports, and editorials spanning molecular genetics, transcription and translation, epigenetics, non-coding RNA, and the molecular basis of disease. Studies using genome editing, sequencing, and computational structure prediction are encouraged.

Intended for molecular biologists, geneticists, biochemists, and translational researchers, the journal emphasizes rigor, reproducibility, and mechanistic insight, and every submission undergoes double-blind peer review.

Accepted articles are published open access under CC-BY 4.0, with authors retaining copyright, and each receives a permanent Crossref DOI. Content is discoverable via OpenAlex and Google Scholar and exposed through OAI-PMH; the journal follows COPE principles.

Subject Coverage

The Journal of Molecular Biology welcomes original research, reviews, and case reports across the following core areas:

Gene Expression and Regulation
transcription factor regulation · gene expression profiling · gene regulatory networks · epigenetic regulation of gene expression · rna polymerase and promoters
Genome Editing and CRISPR
crispr cas9 genome editing · base editing and prime editing · crispr screening single cell · off-target effects crispr · in vivo gene editing delivery
Nucleic Acids: DNA and RNA Biology
dna replication and repair · messenger rna processing · non-coding rna and microrna · rna interference mechanisms · dna methylation and chromatin
Protein Structure and Function
protein folding mechanisms · protein structure prediction alphafold · enzyme structure and function · protein-protein interactions · cryo-em structural biology
Molecular Genetics and Disease
molecular basis of disease · mutation and genetic variation · cancer molecular biology · biomarkers and molecular diagnostics · signal transduction pathways
Methods and Single-Cell Genomics
single cell rna sequencing · next generation sequencing methods · molecular cloning techniques · pcr and qpcr protocols · multi-omics integration

Research Topics

Core subject areas published in The Journal of Molecular Biology — explore related research across our journals.

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Articles

Frequently Asked Questions

What topics does The Journal of Molecular Biology cover?

The journal covers the full breadth of molecular biology, including gene expression and regulation, DNA replication and repair, RNA biology and non-coding RNA, protein structure and function, epigenetics and chromatin, CRISPR genome editing, signal transduction, and the molecular basis of disease. Methods papers on sequencing, single-cell genomics, and structural biology are also welcome.

Who should read or publish in The Journal of Molecular Biology?

It is intended for molecular biologists, geneticists, biochemists, structural and computational biologists, and translational researchers. Authors investigating molecular mechanisms of cellular function, gene regulation, or disease, and readers seeking open-access primary research in these areas, will find the journal a relevant venue.

How do I submit a manuscript to The Journal of Molecular Biology?

Submit through the journal's submission page after preparing your manuscript according to the author guidelines. The journal accepts original research articles, reviews, methods papers, case reports, and editorials in molecular biology. All submissions undergo double-blind peer review.

Is The Journal of Molecular Biology open access, and who holds copyright?

Yes. All accepted articles are published open access under a Creative Commons Attribution (CC-BY 4.0) licence, and authors retain copyright of their work. Articles are freely readable and reusable with attribution worldwide, with no subscription or paywall.

Does each article receive a DOI and how is it indexed?

Every published article is assigned a permanent Crossref DOI for stable citation. Content is discoverable via OpenAlex and Google Scholar and is exposed through an OAI-PMH endpoint for harvesting. The journal is also preparing for wider indexing applications as it grows.

What are the article-processing charges, and are waivers available?

An article-processing charge applies on acceptance to support open-access publication; there are no submission fees. Waivers and discounts are available, including for authors with limited funding. Contact the editorial office for current rates and waiver eligibility before or during submission.

What article types does The Journal of Molecular Biology accept?

The journal accepts original research articles, review articles, methods and protocol papers, short communications, case reports, and editorials. Reviews and methods papers on topics such as CRISPR, single-cell sequencing, and protein structure prediction are especially valuable for building topical depth.

How does peer review work and how is research integrity ensured?

Manuscripts undergo double-blind peer review by qualified reviewers in the relevant subfield. The journal follows COPE ethical principles covering authorship, conflicts of interest, plagiarism, and corrections, and supports data-availability and reproducibility standards to safeguard the scholarly record.

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