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Correspondence to Author: Andreza Ferreira Da Silva, Jessiane Rejane Lima Santos, Samir Buainain Kassar, Müller Ribeiro-Andrade, João Araújo Barros-Neto, Juliana Célia De Farias Santos. 

¹Master in Medical Sciences, Graduate Program in Medical Sciences, School of Medicine, Federal University of Alagoas, Alagoas, Brazil.ORCID: https://orcid.org/0009-0008-5867-0118, E-mail: andesa.silva@fanut.ufal.br
²Master in Human Nutrition, Institute of Biological and Health Sciences, Federal University of Alagoas, Alagoas, Brazil.ORCID: https://orcid.org/0000-0001-9527-4116, E-mail: jessiane.santos@fanut.ufal.br
³PhD in Child and Adolescent Health Centro Universitário de Maceió, Alagoas, Brazil. ORCID: https://orcid.org/0000-0003-1068-6360,E-mail: samirbkr@uol.com.br
⁴PhD in Animal Biosciences Institute of Biological and Health Sciences, Federal University of Alagoas, Alagoas, Brazil,ORCID: https://orcid.org/0000-0002-8235-0359, E-mail: muller.andrade@icbs.ufal.br
⁵PhD in Interactive Processes of Organs and Systems, School of Nutrition, Federal University of Alagoas, Alagoas, Brazil,ORCID: https://orcid.org/0000-0002-7603-1095, E-mail: joao.neto@fanut.ufal.br
⁶PhD in Chemistry and Biotechnology, Graduate Program in Medical Sciences, School of Medicine, Federal University of Alagoas, Alagoas, Brazil,ORCID: https://orcid.org/0000-0003-3679-0158, E-mail: juliana.santos@fanut.ufal.br

Abstract

Introduction: The health profile of patients with chronic kidney disease (CKD) undergoing hemodialysis reflects the interaction between social and uremic factors. With the nutritional transition, sarcopenia has become an increasingly common finding in hemodialysis centers. Objective: To assess the health profile and risk of sarcopenia in CKD patients undergoing hemodialysis in the Agreste region of Alagoas, Brazil.
Method: A cross-sectional study was conducted with hemodialysis patients of both sexes, aged ≥18 years. Socioeconomic, clinical, and anthropometric data were collected after the dialysis session. Sarcopenia risk was estimated using the SARC-F questionnaire. Laboratory data were extracted from medical records.
Results: Among the 300 participants, 58.3% were at risk of sarcopenia. The majority were female (50.7%), comprised of older people (55.7%), and individuals who self-identify as Black people (59.3%). In univariate analysis, a history of hospitalization was associated with a higher risk of sarcopenia (OR = 1.63; p = 0.05). Statistical modeling indicated a higher likelihood of risk in patients with underweight arm circumference (OR = 1.97; p = 0.01), low body mass index (OR = 1.76; p = 0.04), and iron supplementation (OR = 2.02; p < 0.01).
Conclusion: The risk of sarcopenia is high among hemodialysis patients in the Agreste region of Alagoas, particularly in those with nutritional deficits and undergoing iron supplementation.

Citation:

Juliana Célia De Farias Dos Santos, Health Profile And Risk Of Sarcopenia In Patients With Chronic Kidney Disease On Hemodialysis In The Agreste Region Of Alagoas. The Journal of Nephrology 2025.