Competitive physical sports demand rigorous training, increasing the risk of overuse-associated musculoskeletal traumatic injuries followed by a complex and time-consuming healing process with economic effects and potential disability. Tissue healing involves inflammation, molecular and cellular pathway regulation, proliferation, and tissue regeneration. These responses can significantly vary depending on the location and severity of the injury, affecting recovery time, pain intensity, range of motion, and return to sports activity. Despite medical advancements, healing, pain alleviation, regenerative tissue quality, mobility, and quality of life remain challenging.